Lille Score Calculator

Written by Great Medico

Updated September 24, 2026 •2 min read

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One liver score rarely tells the whole story, but the arithmetic can still be useful when its scope is clear. Lille Score Calculator applies the named formula to the entered clinical variables and keeps the limitations visible.

What this calculator does

Lille Score Calculator uses Patient age, Serum albumin, Bilirubin day 0, Bilirubin day 7, Serum creatinine, and Prothrombin time to produce the <0.45 — response range used by this calculator. It only uses the fields shown in this calculator; it does not silently add tests, diagnoses, symptoms, or clinical variables that are absent from the interface. Implements the Lille model after 7 days of corticosteroid therapy for severe alcohol-associated hepatitis.

How to use it

Enter or select Patient age, Serum albumin, Bilirubin day 0, Bilirubin day 7, Serum creatinine, and Prothrombin time. Keep laboratory units consistent and use values from the clinical time point required by the named model. If an input is unknown, it is better to leave the calculation unresolved than to invent a value.

How the calculation works

The Lille model combines age, albumin, day-0 bilirubin, bilirubin change from day 0 to day 7, renal-insufficiency flag, and prothrombin time in a logistic equation. The engine standardizes albumin/bilirubin/creatinine units before calculating the R value and Lille probability.

Example

Using the calculator’s prefilled demonstration values, the primary output is 0.06, labeled “<0.45 — response range”; Bilirubin change (day 0 − day 7) is 119.7 µmol/L and Renal insufficiency flag is No. That sample is useful for checking the calculation path, but real interpretation should use verified measurements from the same clinical or study context.

How to interpret the result

Read <0.45 — response range as the result of the named liver/GI model. Use it for the population and purpose in which the model was validated, and avoid interpreting the number as a stand-alone diagnosis, prognosis, or treatment indication.

Limitations and notes

Cutoffs can differ by disease population and guideline, and lab values can change quickly with treatment or acute illness. Use trends, the correct indication, and confirmatory testing or specialist assessment when the result could change management.